Dietary danger components for recurrent and complex symptomatic kidney stones


To compare dietary factors between incident symptomatic stone supplements and controls, and between incident symptomatic stone supplements, to determine whether dietary factors are predict symptom recurrence.

Patients and methods

We recruited 411 local symptomatic nephrolithiasis patients (validated medical records) and 384 controls who were seen at the Mayo Clinic in Minnesota or Florida as of January 1. 1, 2009 to August 31, 2018. Dietary factors based on Viocare, Inc., food frequency questionnaire administered during an in-person research facility visit. Logistic regression comparing dietary risk factors between incident symptomatic stone supplements and controls. The stonemason incident was monitored for symptom recurrence in the medical record. Cox proportional hazard models estimate the risk of symptom recurrence with dietary factors. Analyzes were adjusted for fluid intake, energy intake, and unrelated risk factors.


In fully adjusted analyses, lower calcium, potassium, caffeine, phytate, and fluid intake were all associated with a higher incidence of incident symptomatic kidney stones. Among those who supplemented with incident ice, 73 experienced a symptom recurrence during a mean 4.1 years of follow-up. Adjusted body mass index, fluid and energy intake, reduced dietary calcium, and lower potassium intake were predictors of kidney stone recurrence. With further adjustment for unrelated risk factors, lower dietary calcium was still a predictor of relapse, but lower potassium was only a predictor of relapse in those who did not. thiazide diuretics or calcium supplements.


Supplementing a stone patient’s rich diet with foods rich in calcium and potassium can help prevent symptomatic kidney stones from recurring.

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